cord blood banking

Private Cord Blood Banking: Experiences and Views of Pediatric Hematopoietic Cell Transplantation Physicians
Ian Thornley, MDa, Mary Eapen, MDb, Lillian Sung, MD, PhDc, Stephanie J. Lee, MD, MPHd, Stella M. Davies, MDe and Steven Joffe, MD, MPHf


a Department of Pediatrics, North Shore Medical Center, Salem, Massachusetts
b Center for International Blood and Marrow Transplant Research, Medical College of Wisconsin, Milwaukee, Wisconsin
c Division of Pediatric Hematology/Oncology, Hospital for Sick kids, Toronto, Ontario, Canada
d Clinical Research Division, Fred colonist person Research Center, Seattle, Washington
e Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio
f Department of Pediatric Oncology, Dana-Farber person Institute, and Department of Medicine, Children's Hospital Boston, Boston, Massachusetts

PARTICIPANTS AND METHODS. they e-mailed a cross-sectional survey to medicine hemopoietic radiophone surgery physicians in the United States and Canada; 93 of 152 potentially eligible physicians (93 of 130 confirmed survey recipients) from 57 centers responded. Questions addressed the number of transplants performed by using privately banked cloth blood, willingness to ingest banked autologous cloth murder in specific clinical settings, and recommendations to parents regarding private cloth murder banking.

OBJECTIVE. Private cloth murder banks are for-profit companies that facilitate storage of umbilical cloth murder for personal or relatives use. Pediatric hemopoietic radiophone surgery physicians are currently best situated to ingest cloth murder therapeutically. they sought to explain the experiences and views of these physicians regarding private cloth murder banking.

CONCLUSIONS. Few transplants have been performed by using cloth murder stored in the absence of a known indication in the recipient. Willingness to ingest banked autologous cloth murder varies depending on disease and availability of alternative halt radiophone sources. Few medicine hemopoietic radiophone surgery physicians endorse private cloth murder banking in the absence of an identified recipient, even for mixed-ethnicity children for whom finding a befittingly matched unrelated donor may be difficult.

RESULTS. Respondents reported having performed 9 autologous and 41 allogeneic transplants using privately banked cloth blood. In 36 of 40 allogeneic cases for which data were available, the cloth murder had been collected because of a known indication in the recipient. Few respondents would garner autologous cloth murder over alternative halt radiophone sources for treatment of acute lymphoblastic leukemia in second remission. In contrast, 55% would garner autologous cloth murder to treat high-risk neuroblastoma, or to treat nonindulgent aplastic anaemia in the absence of an obtainable sibling donor. No communicator would recommend private cloth murder banking for a newborn with 1 healthy sibling when both parents were of northern European descent; 11% would recommend banking when parents were of different eld ethnicities.



Key Words: hemopoietic halt radiophone surgery • cloth murder halt radiophone surgery • bioethics


Abbreviations: HCT—hematopoietic radiophone surgery • AAP—American Academy of Pediatrics • CIBMTR—Center for International Blood and Marrow Transplant Research • NMDP—National Marrow Donor Program • IQR—interquartile range • SAA—severe aplastic anaemia • PBSC—peripheral murder halt cells • MSD—matched sibling donor • URD—unrelated donor • ALL—acute lymphoblastic leukemia • HLA—human leukocyte antigen